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Trends in quality indicators of end-of-life care for women with gynecologic malignancies in Ontario, Canada

Published:September 23, 2022DOI:https://doi.org/10.1016/j.ygyno.2022.09.008

      Highlights

      • Over 40% of gynecologic cancer decedents will die in hospital and half will be hospitalized in their final 30 days of life.
      • Rates of aggressive end-of-life care are unchanged over the past 13 years, which may be an indicator of poor-quality care.
      • Ovarian cancer patients access more aggressive and supportive care resources, while vulvar-vaginal cancer patients use less.
      • Those living in rural or lower income settings are more likely to receive aggressive end-of-life care.
      • Future study of patient and caregiver priorities, and the impact of palliative care on end-of-life outcomes, is needed.

      Abstract

      Objective

      A large body of research has validated several quality indicators of end-of-life (EOL) cancer care, but few have examined these in gynecologic cancer at a population-level. We examined patterns of EOL care quality in patients with gynecologic cancers across 13 years in Ontario, Canada.

      Methods

      We conducted a population-based, retrospective cohort study of gynecologic cancer decedents in Ontario from 2006 to 2018 using linked administrative health care databases. Proportions of quality indices were calculated, including: emergency department (ED) use, hospital or intensive care unit (ICU) admission, chemotherapy ≤14 days of death, cancer-related surgery, tube or intravenous feeds, palliative home visits, and hospital death. We used multivariable logistic regression to examine factors associated with receipt of aggressive and supportive care.

      Results

      There were 16,237 included decedents over the study period; hospital death rates decreased from 47% to 37%, supportive care use rose from 65% to 74%, and aggressive care remained stable (16%). Within 30 days of death, 50% were hospitalized, 5% admitted to ICU, and 67% accessed palliative homecare. Within 14 days of death, 31% visited the ED and 4% received chemotherapy. Patients with vulvovaginal cancers received the lowest rates of aggressive and supportive care. Using multivariable analyses, factors associated with increased aggressive EOL care use included younger age, shorter disease duration, lower income quintiles, and rural residence.

      Conclusions

      Over time, less women dying with gynecologic cancers in Ontario experienced death in hospital, and more accessed supportive care. However, the majority were still hospitalized and a significant proportion received aggressive care in the final 30 days of life.

      Keywords

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