Hormone therapy (HT) in women with gynecologic cancers and in women at high risk for developing a gynecologic cancer: A Society of Gynecologic Oncology (SGO) clinical practice statement

This practice statement has been endorsed by The North American Menopause Society
Published:February 14, 2020DOI:


      • Treatment or prevention of gynecologic cancer often results in induced menopause significantly impacting quality of life.
      • Hormone therapy is underutilized in in these settings despite more severe symptoms with induced menopause.
      • The risk/benefit profile of HT is favorable in most EOC, early stage endometrial, and cervical cancer.
      • HT is not recommended in women with advanced EC, uterine sarcoma, endometrioid or low grade serous ovarian cancer.
      • Lynch syndrome patients and BRCA mutation carriers without history of breast cancer may also use HT to improve QOL.
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