Advertisement

Tumor-derived serum exosomal microRNA as a novel biomarker for high-grade serous carcinoma

      Objectives: High-grade serous cancer (HGSC) is diagnosed at an advanced stage due to the lack of a reliable early detection biomarker. Exosomes are microvesicles, 50–100 nm in size, that form when endosomes fuse with cell membranes and are released into the extracellular space. Modern genomic technology allows researchers to isolate and interrogate circulating serum exosomes. We hypothesize that tumor-derived serum exosomes contain microRNAs (miRNAs) that can serve as novel biomarkers for HGSC.
      To read this article in full you will need to make a payment

      Subscribe:

      Subscribe to Gynecologic Oncology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect