Abstract| Volume 135, ISSUE 2, P383, November 2014

Germline mutations in cancer susceptibility genes in brca1 and brca2 negative families with ovarian and breast cancer

      Objectives: Germline mutations in cancer susceptibility genes other than BRCA1 and BRCA2 (BRCA1/2) are found in approximately 6% of women with ovarian, fallopian tube, or primary peritoneal cancer. Our objective was to sequence BRCA1/2-negative ovarian cancer patients with a family history of ovarian or breast cancer to identify inherited mutations that may explain the familial risk.
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