Abstract
Objectives.
To retrospectively evaluate the accuracy of magnetic resonance (MR) imaging for the
prediction of depth of myometrial invasion in the preoperative assessment of women
with endometrial carcinoma.
Methods.
We retrospectively reviewed the medical records and MR imaging reports of 120 women
with pathologically-proven endometrial carcinoma who underwent preoperative pelvic
MR imaging between June 1997 and February 2006. Tumor signal intensity, the appearance
of the junctional zone (JZ), the presence of large polypoid tumors and leiomyomas
were analyzed. Univariate logistic-regression analysis was performed to identify associations
between incorrect MR staging and the study variables.
Results.
Data from 120 patients were registered for the current study and analyzed. The sensitivity,
specificity and accuracy of the MR imaging in assessment of myometrial invasion among
patients with endometrial carcinoma were: 50.6%, 89.2% and 62.5% respectively. MR
differentiation of deep myometrial invasion from superficial disease had an 83.3%
accuracy (100 of 120 cases). Isointense JZ to myometrium (P<0.001), and the presence of polypoid tumors (P=0.037) on MR imaging were significantly associated with an underestimation of myometrial
invasion by endometrial carcinoma.
Conclusions.
Isointense JZ to myometrium and polypoid tumors are difficult to accurately evaluate
for myometrial invasion of endometrial carcinoma by MR imaging.
Keywords
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Article info
Publication history
Received:
August 23,
2006
Identification
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© 2006 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
