Chronic stress has been shown to be related to dysregulation of a number of physiological systems critical to health maintenance. In contrast, stress moderators have been shown to buffer deleterious effects of stress on the body. Psychological factors such as stress are known to influence activity in the sympathetic nervous system and hypothalamic–pituitary–adrenal axis [
]. The focus of our laboratory has been on measuring stress, social support and disease parameters in patients with gynecologic cancers, using validated self-report questionnaires and objective measures of immune function such as natural killer cell cytotoxicity and production of cytokines.
- Chrousos G.
The concepts of stress and stress system disorders.
JAMA. 1992; 267: 1244-1252
To read this article in full you will need to make a payment
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to Gynecologic Oncology
Already a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
- The concepts of stress and stress system disorders.JAMA. 1992; 267: 1244-1252
- Interleukin-6 and social support in gynecologic cancer patients.Int. J. Behav. Med. 2000; 7: 127-142
- Exposure to physical and psychological stressors elevates plasma interleukin-6: relationship to the activation of hypothalamic–pituitary–adrenal axis.Endocrinology. 1993; 133: 2523-2530
- Interleukin 6 (IL-6) functions as an autocrine growth factor in cervical carcinomas in vitro.Gynecol. Oncol. 1993; 50: 15-19
- Effects of interleukin-6 on in vitro cell attachment, migration, and invasion of human ovarian carcinoma.Anticancer Res. 1997; 17: 337-342
- Life stress, mood disturbance, and elevated interleukin-6 in healthy older women.J. Gerontol. Med. Sci. 1999; 54 A: M1-M6
- Increased serum IL-6 and IL-1 receptor antagonist concentrations in major depression and treatment resistant depression.Cytokine. 1997; 9: 853-858
- Interleukin-6 levels in depressed patients before and after treatment with fluoxetine.Ann. N. Y. Acad. Sci. 1995; 762: 474-476
- Psychosocial factors and interleukin-6 among women with advanced ovarian cancer.Cancer. 2005; 104: 305-313
- The use of religion and other emotion-regulating coping strategies among older adults.Gerontologist. 1988; 28: 303-310
- Religious attendance increases survival by improving and maintaining good health behaviors, mental health, and social relationships.Ann. Behav. Med. 2001; 23: 68-74
- Frequent attendance at religious services and mortality over 28 years.Am. J. Public Health. 1997; 87: 957-961
- Does religious attendance prolong survival? A six-year follow-up study of 3,968 older adults.J. Gerontol. A Biol. Sci. Med. Sci. 1999; 54: M370-M376
- The association of social relationships and activities with mortality: prospective evidence from the Tecumseh Community Health Study.Am. J. Epidemiol. 1982; 116: 123-140
- Religious participation, interleukin-6, and mortality in older adults.Health Psychol. 2004; 23: 465-475
- Vascular endothelial growth factor and social support in patients with ovarian carcinoma.Cancer. 2002; 95: 808-815
- Stress-related mediators stimulate vascular endothelial growth factor secretion by two ovarian cancer cell lines.Clin. Cancer Res. 2003; 9: 4514-4521
☆This report is based on a presentation given at the 4th International Conference on Cervical Cancer.
© 2005 Published by Elsevier Inc. All rights reserved.