Conference Report| Volume 99, ISSUE 3, SUPPLEMENT , S139-S140, December 2005

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Stress, spirituality, and cytokines in aging and cancer

      Chronic stress has been shown to be related to dysregulation of a number of physiological systems critical to health maintenance. In contrast, stress moderators have been shown to buffer deleterious effects of stress on the body. Psychological factors such as stress are known to influence activity in the sympathetic nervous system and hypothalamic–pituitary–adrenal axis [
      • Chrousos G.
      The concepts of stress and stress system disorders.
      ]. The focus of our laboratory has been on measuring stress, social support and disease parameters in patients with gynecologic cancers, using validated self-report questionnaires and objective measures of immune function such as natural killer cell cytotoxicity and production of cytokines.
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