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Abstract
Objective. To examine the feasibility and safety of a low anterior resection of the rectosigmoid
plus adjacent pelvic tumour as part of primary cytoreduction for ovarian cancer.
Methods. This study included 65 consecutive patients with primary ovarian cancer who had debulking
surgery from 1996 through 2000. All patients underwent an en bloc resection of ovarian cancer and a rectosigmoid resection followed by an end-to-end
anastomosis. Parameters for safety and efficacy were considered as primary statistical
endpoints for the aim of this analysis.
Results. Postoperative residual tumour was nil, <1 cm, and >1 cm in 14, 34, and 14 patients,
respectively. The median postoperative hospital stay was 11 days (range, 6 to 50 days).
Intraoperative complications included an injury to the urinary bladder in one patient.
Postoperative complications included wound complications (n = 14, 21.5%), septicemia (n = 9, 13.8%), cardiac complications (n = 7, 10.8%), thromboembolic complications (n = 5, 7.7%), ileus (n = 2, 3.1%), anastomotic leak (n = 2, 3.1%), and fistula (n = 1, 1.5%). Reasons for a reoperation during the same admission included repair of
an anastomotic leak (n = 1), postoperative hemorrhage (n = 1), and wound debridement (n = 1). Wound complications, septicemia, and anastomotic leak formation were more frequent
in patients who had a serum albumin level of ≤30 g/L preoperatively. There was one
surgically related mortality in a patient who died from a cerebral vascular accident
2 days postoperatively.
Conclusions. An en bloc resection as part of primary cytoreductive surgery for ovarian cancer is effective
and its morbidity is acceptably low.
Keywords
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Article info
Publication history
Received:
April 3,
2001
Identification
Copyright
© 2001 Academic Press. Published by Elsevier Inc. All rights reserved.
